FROM MOLECULE DISCOVERY TO COMPLETE FILL AND FINISH
Each stage of bioprocessing is influenced by the steps preceding it. You're constantly striving to achieve higher production yields, which influence manufacturing costs. The following considerations are important to weigh:
- Selecting the correct expression system
- Choosing the right medium and feed for your bioreactor to achieve maximum cell density and productivity
- Capturing, clarifying, and concentrating the target protein efficiently
- Obtaining the purified protein through downstream processes
- Packaging the protein formulation during final fill in the required configuration
Avantor’s bioprocessing solutions focus on what matters most for your operations. We provide a unique combination of industry expertise with the broadest portfolio of products and materials engineered and manufactured to satisfy the highest quality standards and regulatory requirements for your final product – whether it is a vaccine, monoclonal antibody, recombinant protein, cell therapy, or gene therapy.
As Avantor’s channel brand, VWR, part of Avantor provides you with an integrated, seamless purchasing experience that is optimized for the way you do business. Access top industry brands through VWR, part of Avantor for an even broader selection of media components, animal sera, buffers, process biochemicals, excipients and single-use solutions to address upstream and downstream processes as well as final fill formulations.
J.T.Baker® BAKERBOND® PROchievA™ protein A chromatography resins
From production chemicals to single-use assemblies, our products address your need to maintain quality, activity, and stability throughout the entire process for monoclonal antibodies – the largest sector in the biologics market.
Recombinant proteins are manufactured using microbial (E. coli) expression systems. Learn about our products for recombinant proteins manufacturing, including fermentation media and chromatography resins.
Primarily developed to target infectious diseases, new vaccine developments are now focusing on immuno-oncology applications. Learn about our products for vaccines manufacturing, such as animal sera and buffer components.
Cell therapies are offering new hope for patients in the fight against life-altering diseases like cancer. Learn about cell culture media and sera, fill and finish excipients and more products we offer for cell therapies manufacturing.
Gene therapies offer the prospect of curative benefits to patients with genetic or acquired diseases. From fermentation media to culture Plasma DNA vectors, and purification of CAR vectors used to engineer T-cells, we have what you need.
Enhance the effectiveness of your products and streamline your biopharmaceutical manufacturing processes with the J.T.Baker® Direct Dispense packaging system...
Our process water filtration systems deliver critical filtration at high flow rates for cooling water systems in any type of manufacturing plant...
Reduce downstream turnaround times by optimizing resin and buffer selections, enhancing yield and purity and decreasing process times.