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Anti-RAD50 Rabbit Polyclonal Antibody
Anti-RAD50 Rabbit Polyclonal Antibody
Catalog #: 89351-524
Supplier:  Genetex
Anti-RAD50 Rabbit Polyclonal Antibody
Catalog #: 89351-524
Supplier:  Genetex
Price
$969.60
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Unit of Measure Each (100µl)
Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.
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Specifications

  • Antibody type:
    Primary
  • Antigen name:
    RAD50 homolog
  • Clonality:
    Polyclonal
  • Gene ID:
    19360
  • Host:
    Rabbit
  • Isotype:
    IgG
  • Reactivity:
    Human
  • Antigen symbol:
    RAD50
  • Conjugation:
    Unconjugated
  • ImmunoPrecipitation:
    Yes
  • Western blot:
    Yes
  • Antigen synonyms:
    DNA repair protein RAD50,
    RAD50 homolog (S cerevisiae),
    RAD50 PEN,
    hsRAD50,
    hRad50,
    Mrell,
    Truncated RAD50 protein,
    RAD50 2,
    Rad50l
  • Storage buffer:
    serum with 0.02% sodium azide
  • Storage temperature:
    Keep as concentrated solution, aliquot and store at 4°C.
  • Immunogen:
    C-terminus of mRad50 (604 amino acids) (Mouse).
  • Tested applications:
    IP, WB
  • Purification:
    Whole antiserum
  • Cat. no.:
    89351-524

Specifications

About this item

Rad50 is a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.

IP: Use 5 ?l for 3-4 X 10^6 cells. WB: Use at a dilution of 1/2000. Predicted molecular weight: 153 kDa in human cells. Has not been shown to work in IF. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.

Type: Primary
Antigen: RAD50
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human

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