Anti-RAD50 Rabbit Polyclonal Antibody

Supplier: Genetex
89351-524EA 927.84 CAD
Anti-RAD50 Rabbit Polyclonal Antibody
Rad50 is a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.

IP: Use 5 ?l for 3-4 X 10^6 cells. WB: Use at a dilution of 1/2000. Predicted molecular weight: 153 kDa in human cells. Has not been shown to work in IF. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.

Type: Primary
Antigen: RAD50
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human
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