Anti-MDM2 Rabbit Polyclonal Antibody

89351-116EA 518.15 CAD
Anti-MDM2 Rabbit Polyclonal Antibody
Human homolog of murine double minute-2 (MDM2) and p53 function in mutual regulation: activation of p53 results in expression of MDM2 which consequently inhibits the ability of wild type p53 to stimulate expression of target genes. MDM2 is frequently overexpressed in the nuclei of soft tissue sarcomas, and to a much lesser extent in a wide variety of malignancies of bladder, breast, testes, cervix, glial cells.

Type: Primary
Antigen: MDM2
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human
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