Anti-MPO Rabbit Polyclonal Antibody

Supplier: GeneTex

89361-148EA 565.64 CAD
Anti-MPO Rabbit Polyclonal Antibody
Myeloperoxidase is a hemoprotein that is abundantly expressed in neutrophils and secreted during their activation. Native MPO is represented as a covalently bound tetrameric complex of two glycosylated alpha chains (MW 59 - 64 kDa) and two unglycosylated beta chains (MW 14 kDa) with total MW 150 kDa and theoretical pI 9.2. Traditionally MPO was considered as a main target of anti-neutrophil cytoplasm antibodies (ANCA), the serological markers for certain systemic vasculities e.g. periarteriitis nodosa, microscopic polyarteriitis and pulmonary eosinophilic granulomatosis (Churg-Strauss syndrome). Low to moderate anti-MPO autoantibody levels are also reported in rheumatoid arthritis.

Suitable for immunoblotting (western or dot blot), ELISA and most immunological methods requiring high titer and specificity. Optimal titers for applications should be determined by the researcher.

Type: Primary
Antigen: MPO
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human
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