Anti-CRYAB Rabbit Monoclonal Antibody

GTX62094
89364-314EA 556.26 CAD
89364-314
Anti-CRYAB Rabbit Monoclonal Antibody
Alpha B Crystallin, first identified as a structural component of the vertebrate eye lens, is expressed at high levels in lens and at lower levels in a number of other tissues, most notably cardiac and skeletal muscle, kidney, and brain . It is a major protein component of Rosenthal fibers, which massively accumulate in the brains of patients suffering from Alexander's disease . The major phosphorylation site of Alpha B Crystallin in brains of patients with Alexander's disease or Alzheimer's disease as well as in aged controls is Serine 59 . Racemization, isomerization, and oxidation of Alpha B Crystallin are said to occur spontaneously in the aging process .

Type: Primary
Antigen: CRYAB
Clonality: Monoclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity:
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