Anti-APC Rabbit Monoclonal Antibody

89363-936EA 556.26 CAD
Anti-APC Rabbit Monoclonal Antibody
Adenomatous polyposis coli (APC) is a protein that plays a critical role in several cellular processes. APC is a tumor suppressor, regulates cell division, helps ensure that the number of chromosomes in a cell is correct following cell division and associates with other proteins involved in cell attachment and signaling . APC regulates β-catenin levels through Wnt-signaling and is involved in actin cytoskeletal integrity, cell-cell adhesion and cell migration . Mutations cause the production of an APC protein that is abnormally short and nonfunctional. Defects in APC are a cause of familial aenomatous polyposis (FAP), Turcot syndrome, medulloblastoma (MDB), and other cancers. (4-6)

Type: Primary
Antigen: APC
Clonality: Monoclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human
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