Anti-APRIL Mouse Monoclonal Antibody [clone: Aprily-1]

Supplier: GeneTex
89360-150EA 925.14 CAD
Anti-APRIL Mouse Monoclonal Antibody [clone: Aprily-1]
Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated APRIL (for A PRoliferation-Inducing Ligand), TALL2 (for TNF and ApoL-related Leukocyte-expressed Ligand 2), and TRDL 1a (for TNF related death ligand 1a) in human and mouse. Two receptors for APRIL were recently identified and designated TACI and BCMA. APRIL stimulates B and T cell proliferation, triggers humoral immune responses, activates NF-kB, and induces cell death. APRIL and its close relative of BlyS and their receptors BCMA and TACI are involved in diseases of autoimmunity and cancer.

For FACS: Use at a concentration of 10 ?g/ml. This antibody also works for intracellular FC staining. For WB: Use at a concentration of 1 ?g/ml. Not tested in other applications. Optimal dilutions/concentrations should be determined by the researcher.

Type: Primary
Antigen: APRIL
Clonality: Monoclonal
Clone: Aprily-1
Conjugation: Unconjugated
Host: Mouse
Isotype: IgG1
Reactivity: Human
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