Anti-APRIL Rat Monoclonal Antibody [clone: Sacha-1]

Supplier: GeneTex

89351-216EA 699.56 CAD
Anti-APRIL Rat Monoclonal Antibody [clone: Sacha-1]
Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated APRIL (for A PRoliferation-Inducing Ligand), TALL2 (for TNF and ApoL-related Leukocyte-expressed Ligand 2), and TRDL 1a (for TNF related death ligand 1a) in human and mouse. Two receptors for APRIL were recently identified and designated TACI and BCMA. APRIL stimulates B and T cell proliferation, triggers humoral immune responses, activates NF-kB, and induces cell death. APRIL and its close relative of BlyS and their receptors BCMA and TACI are involved in diseases of autoimmunity and cancer.

For FACS: Use at a concentration of 1 ?g/ml. For ICC: Use at a concentration of 5 ?g/ml. Not tested in other applications. Optimal dilutions/concentrations should be determined by the researcher.

Type: Primary
Antigen: APRIL
Clonality: Monoclonal
Conjugation: Unconjugated
Host: Rat
Isotype: IgG2a
Reactivity: Human
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