Anti-BCL-2 Related A1/BFL1 Rabbit Monoclonal Antibody

89363-904EA 556.26 CAD
Anti-BCL-2 Related A1/BFL1 Rabbit Monoclonal Antibody
Bcl-2 related protein A1; also known as Bcl2A1 and Bfl1, is an anti-apoptotic Bcl-2 family member preferentially expressed in hematopoietic and endothelial cells . Bfl1 is involved in a variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. Expression of Bfl1 is stimulated by NF-kB in response to inflammatory stimuli and up-regulated by TNF-alpha, IL1-beta, IGF1, GMC-SF, CD40 and phorbol ester . Bfl1 has also been shown to reduce the release of pro-apoptotic cytochrome c from mitochondria, block caspase activation and suppress apoptosis induced by p53 .

Type: Primary
Antigen: BCL-2 Related A1/BFL1
Clonality: Monoclonal
Host: Rabbit
Isotype: IgG
Reactivity: Human
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