Anti-C/EBP alpha Rabbit Monoclonal Antibody

89363-940EA 585.93 CAD
Anti-C/EBP alpha Rabbit Monoclonal Antibody
CCAAT/enhancer-binding proteins (C/EBP) consist of a family of transcription factors that play an important role in regulating the balance between cell growth & differentiation. The various isoforms of C/EBP (α,β,γ,δ,ε, ζ ) exhibit similar DNA-binding specificities and contain a leucine zipper dimerization domain . C/EBP alpha can form heterodimers with related protein C/EBP beta and gamma. C/EBP alpha directly interacts with CDK2and CDK4 and arrests cell proliferation by inhibiting these kinases . C/EBP alpha has been shown to bind to the promoter and modulate the expression of leptin, a protein that plays an important role in body weight homeostasis . C/EBP alpha also has prominent antimitotic activity and may play a role of a tumor suppressor .

Type: Primary
Antigen: C/EBP alpha
Clonality: Monoclonal
Host: Rabbit
Isotype: IgG
Reactivity: Human
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