Anti-CAV1 Rabbit Monoclonal Antibody

89364-218EA 585.93 CAD
Anti-CAV1 Rabbit Monoclonal Antibody
Caveolins make up a family of proteins that are principal structural components of hairpin-like domains in the plasma membrane . It is believed that caveolins serve as scaffolding proteins for the integration of signal transduction. Three members of caveolins (caveolin-1, -2 and -3) have been identified, possessing different tissue distributions . Caveolins interact with multiple signaling molecules, such as the G-protein alpha subunit , tyrosine kinase receptors, PKCs, Src family tyrosine kinases and eNOS . Caveolin-1 has been implicated in the pathogenesis of mammary epithelial cell hyperplasia . Endothelial cell (EC) migration is a critical event during multiple physiological and pathological processes. The phosphorylatable Tyr14 residue of caveolin-1 is required for polarization of the protein during transmigration but does not alter polarization during planar movement.

Type: Primary
Antigen: CAV1
Clonality: Monoclonal
Conjugation: Unconjugated
Host: Rabbit
Reactivity: Human
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