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Specifications
- Antibody type:Primary
- Antigen name:Chromobox Homolog 1
- Clonality:Polyclonal
- Gene ID:10951
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human
- Antigen symbol:CBX1
- Conjugation:Unconjugated
- ImmunoChemistry:Yes
- Western blot:Yes
- Antigen synonyms:heterochromatin protein p25 beta,HP1Hs-beta,modifier 1 protein,HGNC:1551,p25beta,HP1Hsbeta,HP1-BETA,heterochromatin protein 1-beta,MOD1,chromobox homolog 1 (HP1 beta homolog Drosophila ),M31,chromobox homolog 1 (Drosophila HP1 beta),CBX
- Storage buffer:0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
- Molecular weight:21 kDa
- Storage temperature:Keep as concentrated solution. Aliquot and store at –20 °C or below. Avoid multiple freeze-thaw cycles.
- Concentration:0.54 mg/ml
- Immunogen:Recombinant protein encompassing a sequence within the center region of human CBX1 / HP1 beta. The exact sequence is proprietary.
- Tested applications:IHC-P
- Purification:Purified by antigen-affinity chromatography.
- Cat. no.:89358-338
Specifications
About this item
This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq]
Suggested starting dilutions are as follows: WB: 1:500-1:3000, IHC-P: 1:100-1:1000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Type: Primary
Antigen: CBX1 / HP1 beta
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: Human