Anti-CCKAR Rabbit Polyclonal Antibody

Supplier: GeneTex

89367-324EA 782.56 CAD
Anti-CCKAR Rabbit Polyclonal Antibody
The cholecystokinin (CCK) family of peptide hormones have been implicated in numerous important physiologic events. These appear to be mediated through 2 general classes of receptors, A (CCKAR)and B (CCKBR), based on their binding affinities for CCK/gastrin family peptides. Through binding to class A receptors, CCK is a major physiologic mediator of gallbladder contraction and pancreatic enzyme secretion. It appears to play a role in slowing gastric emptying, relaxation of the sphincter of Oddi, and potentiation of insulin secretion. Further, it has been implicated as a mediator of pancreatic growth and tumorigenesis. Class A receptors have also been described in the anterior pituitary, myenteric plexus, and regions of the central nervous system, where they have been implicated in the pathogenesis of feeding disorders, Parkinson disease, schizophrenia, and drug addiction.

WB: Use at a dilution of 1/2000. Detects a band of approximately 48 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.

Type: Primary
Antigen: CCKAR
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Reactivity: Guinea Pig
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