Anti-CD11B Mouse Monoclonal Antibody [clone: MEM-174]

Supplier: Genetex

89360-956EA 624.75 CAD
Anti-CD11B Mouse Monoclonal Antibody [clone: MEM-174]
CD11b is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. CD11b is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.

Recommended dilutions: FACS: Use at an assay dependant concentration. IP: Immunoprecipitation with the antibody was successfuly performed using immuno-affinity sorbents (minicolumns). The final immunosorbent should contain 1-5 mg of antibody/1 ml of sorbent gel (e.g. agarose beads). Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.

Type: Primary
Antigen: CD11B
Clonality: Monoclonal
Clone: MEM-174
Conjugation: Unconjugated
Host: Mouse
Reactivity: Human
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