Anti-CD3 Mouse Monoclonal Antibody [clone: UCHT1]

Supplier: GeneTex

89360-738EA 656.24 CAD
Anti-CD3 Mouse Monoclonal Antibody [clone: UCHT1]
T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits CD3 gamma, CD3 delta, CD3 epsilon and CD3 zeta. These CD3 subunits are structurally related members of the immunoglobulins super family encoded by closely linked genes on human chromosome 11. The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules. This association is mediated at least in part by a double tyrosine-based motif present in a single copy in the CD3 subunits. CD3 may play a role in TCR-induced growth arrest, cell survival and proliferation.

This antibody is not suitable for use on paraffin sections.

Type: Primary
Antigen: CD3
Clonality: Monoclonal
Clone: UCHT1
Conjugation: Unconjugated
Host: Mouse
Isotype: IgG1
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