Anti-CIAP1 Rabbit Polyclonal Antibody

Supplier: GeneTex

89361-238EA 640.91 CAD
Anti-CIAP1 Rabbit Polyclonal Antibody
Apoptosis can be inhibited by a group of proteins called inhibitors of apoptosis (IAPs). These proteins contain a BIR (baculovirus IAP repeat) domain near the amino-terminus. The BIR domain can bind some caspases. Many members of the IAP family of proteins block proteolytic activation of caspase-3 and ~7. For example, XIAP, cIAP 1 and cIAP 2 appear to block cytochrome c-induced activation of caspase-9, thereby preventing initiation of the caspase cascade. Since cIAP 1 and cIAP 2 were first identified as components in the cytosolic death domain-induced complex associated with the TNF family of receptors, they may inhibit apoptosis by additional mechanisms.

WB: Use at a concentration of 1 ?g/ml. In Western blot, this antibody detects a band of approximately 72 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.

Type: Primary
Antigen: CIAP1
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
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