Anti-CLTC Mouse Monoclonal Antibody [clone: 3F133]

Supplier: GeneTex

GTX14409
89359-994EA 718.02 CAD
89359-994
Anti-CLTC Mouse Monoclonal Antibody [clone: 3F133]
Antibodies
Various cell types express both forms of clathrin LC in different relative levels. LCs are randomly distributed on clathrin triskelion, resulting in four types of clathrin triskelion with different LC composition (3LCa, 2LCa 1LCb, 2LCb-1LCa, 3LCb). In most cells, the LCa form is dominant. In contrast, cells with a regulated secretory pathway contain more LCb than LCa, suggesting that LCb may play a role in the specialized clathrin functions in these cells. Neuronal cells, express splicing variants of both LCa and LCb. A distinguishing feature of the LCb light chain is its ability to be phosphorylated by a casein kinase, at a site which is not present in the LCa sequence.

Recommended Starting Dilutions:ICC: Use at an assay dependent dilution. IF: Use at an assay dependent dilution. IHC-P: Use at a concentration of 1 - 2 ?g/ml. IP: Use at an assay dependent dilution. WB: Use at a concentration of 1 - 2 ?g/ml. Predicted molecular weight: 28 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.

Type: Primary
Antigen: CLTC
Clonality: Monoclonal
Clone: 3F133
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype:
Reactivity:
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