Anti-CCND1 Rabbit Polyclonal Antibody

Supplier: GeneTex

89367-528EA 826.83 CAD
Anti-CCND1 Rabbit Polyclonal Antibody
During each cell cycle cyclins undergo periodic accumulation and destruction. As key regulators of the cell cycle the cyclins control important transitions by activating Cdks. Early in the G1 phase of the cell cycle cyclin D1 induction is followed by cyclin E induction. This sequential progression is marked early on in G1 by the activation of Cdk4 and in mid to late G1 by the activation of Cdk2 and the hyperphosphorylation of pRB. The final transition into S phase is thought to be dependent on the increased expression and association of cyclin E and Cdk2.

  • Western blot - 1:500 to 1:1000. A band at approximately 34kD corresponds to Cyclin D1. Higher MW bands might be seen corresponding to precipitating IgG. ELISA - 1:500 to 1:2,000. Optimal titers for other applications should be determined by the researcher.

Type: Primary
Antigen: CCND1
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Reactivity: Human
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