Anti-ITGA2B Mouse Monoclonal Antibody (FITC) [clone: SZ.22]

Supplier: GeneTex
89360-668EA 1005.2 CAD
Anti-ITGA2B Mouse Monoclonal Antibody (FITC) [clone: SZ.22]
Integrin alpha 2b (CD41) is a calcium-dependent, noncovalently associated heterodimer and contains a heavy chain (GPIIb-alpha) and a light chain (GPIIb-beta) linked by a single disulfide bond. The Integrin alpha 2B chain interacts with the Integrin beta 3 subunit/CD61 to form the platelet glycoprotein complex, gpIIb/IIIa. It is expressed on platelets and megakaryocytes. Ligands for the gpIIb/IIIa heterodimer include fibrinogen, von Willebrand factor, fibronectin, vitronectin, and thrombospondin. The gpIIb/IIIa complex is the major Integrin on platelets and is important for platelet adhesion and aggregation.

FACS: Use 20?l for 10^6 cells. IHC-Fr: 1/50 - 1/100. WB: Use at an assay dependent dilution. Predicted molecular weight: 113 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.

Type: Primary
Antigen: ITGA2B
Clonality: Monoclonal
Clone: SZ.22
Conjugation: FITC
Host: Mouse
Isotype: IgG1
Reactivity: Human
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