Anti-MAPT Rabbit Monoclonal Antibody

GTX62199
89364-348EA 556.26 CAD
89364-348
Anti-MAPT Rabbit Monoclonal Antibody
Tau is a microtubule binding protein that promotes microtubule assembly and stability. Tau is found to be the major component of the paired helical filaments (PHFs) found in the brains of patients with Alzheimer disease (AD) . Tau is hyperphosphorylated in PHFs, and specific phosphorylation sites have been implicated in the loss of Taus association with the membrane cortex during AD disease state, including Ser 199/202, Thr 231, and Ser 393/404 . Glycogen synthase kinase-3, or GSK-3, phosphorylates Tau on Ser 396 .

Type: Primary
Antigen: MAPT
Clonality: Monoclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human
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