Anti-DAP5 Mouse Monoclonal Antibody [clone: 39C534.1]

Supplier: GeneTex
89358-994EA 992.84 CAD
Anti-DAP5 Mouse Monoclonal Antibody [clone: 39C534.1]
Death Associated Protein 5 (DAP5) is a 97 kDa protein with high amino acid sequence homology to Eukaryotic Translation Initiation Factor 4G (eIF4G). Compared with eIF4G, DAP5 lacks the N-terminal region necessary for cap-dependent translation and has a unique C-terminal part functioning as a regulator for interferon-gamma induced cell death. During apoptosis, DAP5 is cleaved at Asp790. The C-terminal truncated form of DAP5 functions as a cap-independent translation initiation factor responsible for the mediation of its own translation during apoptosis.

WB: Use at a concentration of 1 - 2 ?g/ml. Detects a band of approximately 97 kDa. For optimal results, primary antibody incubations should be performed at room temperature. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.

Type: Primary
Antigen: DAP5
Clonality: Monoclonal
Clone: 39C534.1
Conjugation: Unconjugated
Host: Mouse
Isotype: IgG
Reactivity: Human
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