Anti-CDH1 Chicken Polyclonal Antibody

GTX14015
89367-232EA 643.47 CAD
89367-232
Anti-CDH1 Chicken Polyclonal Antibody
One of the epithelial cell adhesion molecules, E Cadherin, plays an important role in the formation of cell-cell contacts in epithelia irrespective their origin form ecto-, meso- or endodermal tissue. This early adhesion event between epithelial cells is a prerequisite for the assembly of all elements of the junctional complex. Furthermore, E Cadherin plays a crucial role in the maintenance of the epithelial junctional complex and is as such an important molecule in maintaining epithelial integrity. Over 90% of the malignant tumors are carcimomas. One of the prerequisites for the release of carcinoma cells from the primary site might be a defect in intercellular adhesion mediated by the absence of E Cadherin expression. Therefore, the expression of E Cadherin might be an important parameter for the determination of the invasive potential of epithelial neoplasms, and for the transition of a benign to a malignant neoplasm.

Type: Primary
Antigen: CDH1
Clonality: Polyclonal
Clone: 0
Conjugation: Unconjugated
Epitope:
Host: Chicken
Isotype: IgY
Reactivity:
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