Anti-F Hemoglobin Sheep Polyclonal Antibody

GTX19365
89351-474EA 650.28 CAD
89351-474
Anti-F Hemoglobin Sheep Polyclonal Antibody
The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'

Type: Primary
Antigen: F Hemoglobin
Clonality: Polyclonal
Clone:
Conjugation:
Epitope:
Host: Sheep
Isotype: IgG
Reactivity: Human
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