Anti-GSF3R Mouse Monoclonal Antibody [clone: S1390]

Supplier: GeneTex
89360-616EA 907.77 CAD
Anti-GSF3R Mouse Monoclonal Antibody [clone: S1390]
Granulocyte colony stimulating factors promotes survival, proliferation and differentiation of bone marrow precursor cells. GCSF is a lineage restricted hematopoietic growth factor, stimulating final mitotic divisions and terminal cellular maturation of partially differentiated hematopoietic progenitors. Human GCSF binds and activates a GCSF receptor, a 130 kDA to 150 kDa glycoprotein single chain receptor. The GCSF receptor (CD114) has been classified as a member of the hematopoietic (cytokine) receptor family, cytokine receptor class I, or the gp 130 related cytokine receptor family (although it does not apparently bind to gp 130). GCSF receptors can be found on neutrophils, myeloid leukemia cells that respond to GCSF, bone marrow cells of neutrophilic granulocyte lineage, and on placental trophoblasts. In addition, a soluble form is also expressed.

ELISA: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Predicted molecular weight: 92 kDa. Immunoblotting: Recognizes denatured G-CSFR following SDS-PAGE and blotting of 200 ug of cell lysate or following immunoprecipitation with polyclonal antibody followed by immunoblotting. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.

Type: Primary
Antigen: CSF3R
Clonality: Monoclonal
Clone: S1390
Conjugation: Unconjugated
Host: Mouse
Isotype: IgG2b
Reactivity: Human
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