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Specifications
- Antibody type:Primary
- Antigen name:Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B-Cells Inhibitor, Zeta
- Clonality:Polyclonal
- Gene ID:64332
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human
- Antigen symbol:NFKBIZ
- Conjugation:Unconjugated
- Western blot:Yes
- Antigen synonyms:IKBZ,INAP,MAIL
- Storage buffer:0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
- Molecular weight:78 kDa
- Storage temperature:Keep as concentrated solution. Aliquot and store at –20 °C or below. Avoid multiple freeze-thaw cycles.
- Concentration:0.92 mg/ml
- Immunogen:Recombinant protein encompassing a sequence within the center region of human IKB zeta. The exact sequence is proprietary.
- Tested applications:WB
- Purification:Purified by antigen-affinity chromatography.
- Cat. no.:89358-702
Specifications
About this item
This gene is a member of the ankyrin-repeat family and is induced by lipopolysaccharide (LPS). The C-terminal portion of the encoded product which contains the ankyrin repeats, shares high sequence similarity with the I kappa B family of proteins. The latter are known to play a role in inflammatory responses to LPS by their interaction with NF-B proteins through ankyrin-repeat domains. Studies in mouse indicate that this gene product is one of the nuclear I kappa B proteins and an activator of IL-6 production. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Suggested starting dilutions are as follows: WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Type: Primary
Antigen: NFKBIZ
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human