Anti-IL12 Rat Monoclonal Antibody

Supplier: GeneTex
89363-466EA 1039.15 CAD
Anti-IL12 Rat Monoclonal Antibody
Interleukin 12 (IL12) can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine activated killer cells, and stimulate the production of IFN gamma by resting PBMC. IL12 induces IFN gamma, TNF alpha production in T and NK cells; costimulation of PBL proliferation; proliferation/differentiation of TH1 T lymphocytes. It is downregulated by IL10; homodimeric p40 antagonistic to functional p70 heterodimer. IL12R beta 1 binds p40 but when dimeric with IL12R beta 2 binds p35.

Type: Primary
Antigen: IL12
Clonality: Monoclonal
Conjugation: Unconjugated
Host: Rat
Isotype: IgG2a
Reactivity: Mouse
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