Anti-IL4 Mouse Monoclonal Antibody [clone: 8F12]

Supplier: GeneTex
89359-848EA 785.18 CAD
Anti-IL4 Mouse Monoclonal Antibody [clone: 8F12]
The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

FACS: Use at an assay dependent dilution. ICC: Use at an assay dependent dilution. Neut: Use at an assay dependent dilution. A preparation of clone 8F12 that has no preservatives or stabilizers and has a low content of endotoxin is recommended for this application. WB: Use at an assay dependent dilution. Predicted molecular weight: 18.4 kDa. /this antibody was found to react equally well with native and denatured amounts of human IL4 lower than 10 ng. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.

Type: Primary
Antigen: IL4
Clonality: Monoclonal
Clone: 8F12
Conjugation: Unconjugated
Host: Mouse
Isotype: IgG1
Reactivity: Human
Order Now

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Learn more About VWR