Anti-IL4 Rat Monoclonal Antibody [clone: BVD4-1D11]

Supplier: GeneTex
89358-290EA 609.78 CAD
Anti-IL4 Rat Monoclonal Antibody [clone: BVD4-1D11]
The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Recommended Starting Dilutions:ELISA: 1 ug/ml - 5 ug/mlWestern Blotting: 1 ug/ml - 5 ug/mlFlow Cytometry: 1/10 - 1/50Not tested in other applications. Optimal dilution / concentration should be determined by the end user.

Type: Primary
Antigen: IL4
Clonality: Monoclonal
Conjugation: Unconjugated
Host: Rat
Isotype: IgG2b
Reactivity: Mouse
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