Anti-MCM7 Mouse Monoclonal Antibody [clone: 47DC141]

Supplier: GeneTex
89367-056EA 706.94 CAD
Anti-MCM7 Mouse Monoclonal Antibody [clone: 47DC141]
hCDC47 is a human member of the MCM family, which allows DNA to replicate once per cell cycle. In quiescent cells, human MCM7 (hMCM7) mRNA is almost undetectable. Stimulation of cells to enter the cell cycle results in induction of hMCM7 expression. The hCDC47 protein expression and localization is found in nuclei of the proliferative components of normal lymph nodes, bone marrow, epidermis and mucosa. Malignant tumors from several organs contained more nuclearhCDC47 positive cells than their normal counterparts. These results indicate that hCDC47 may play a role in normal and neoplastic cell growth in vivo.

For IF: Use at an assay dependent dilution. For IHC-P: Use at a concentration of 0 . 5 - 1 . 0 mg / m l f o r 3 0 m i n a t R T. Requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 minutes followed by cooling at RT for 20 min. For IP (native and denatured) Use protein G: Use at a concentration of 2 ?g/mg protein lysate. For WB: Use at a concentration of 1-2 ug/ml for 2hrs at RT. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.

Type: Primary
Antigen: MCM7
Clonality: Monoclonal
Conjugation: Unconjugated
Host: Mouse
Isotype: IgG1
Reactivity: Dog
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