Anti-MSH2 Rabbit Polyclonal Antibody

Supplier: GeneTex
89360-238EA 673.17 CAD
Anti-MSH2 Rabbit Polyclonal Antibody
MSH2 is involved in DNA repair as a mismatch repair protein, and mutations of MSH2 are found in approximately 50% of inherited non polyposis colorectal carcinoma (HNPCC) (Lynch syndrome) cases. HNPCC is an autosomal, dominantly inherited disease associated with marked increase in cancer susceptibility. It is characterized by a familial predisposition to early onset colorectal carcinoma and extra-colonic cancers of the gastrointestinal, urological and female reproductive tracts. HNPCC is reported to be the most common form of inherited colorectal cancer in the western world.

For IHC-Fr: Use at a concentration of 2 ?g/ml. For IHC-P and IP: Use at an assay dependent dilution. For WB: Use at a concentration of 1 - 1.5 ?g/ml. Predicted molecular weight: 100 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the researcher.

Type: Primary
Antigen: MSH2
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human
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