Anti-MSH2 Mouse Monoclonal Antibody [clone: 25D12]

Supplier: GeneTex
89351-768EA 694.86 CAD
Anti-MSH2 Mouse Monoclonal Antibody [clone: 25D12]
MSH2 protein is involved in the initial recognition of mismatched nucleotides during the post replication mismatch repair process. Loss of MSH2 function leads to the accumulation of replication errors, which in turn may be responsible for the multiple mutations required for multistage carcinogenesis.

IHC: This antibody may be diluted to a titer of 1:10-1:25 in an ABC method. We suggest an incubation period of 60 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation conditions and antibody dilutions should be determined by the user. Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining.

Type: Primary
Antigen: MSH2
Clonality: Monoclonal
Clone: 25D12
Conjugation: Unconjugated
Host: Mouse
Isotype: IgG1
Reactivity: Human
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