Oct2 is a transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Oct2 regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. It also modulates transcription transactivation by NR3C1, AR and PGR. Oct2 is B-cell specific, belongs to the POU transcription factor family class-2 subfamily and contains 1 homeobox domain.
IHC-P: Use at a dilution of 1/50. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. IP: Use at a dilution of 2 ?g/mg protein lysate. WB: Use at a concentration of 1 - 2 ?g/ml. Predicted molecular weight: 51 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.