Anti-P21 RAS Mouse Monoclonal Antibody

89351-290EA 443.06 CAD
Anti-P21 RAS Mouse Monoclonal Antibody
The human ras gene family consists of three identified members which encode proteins of 21 kDa. Human c-H-ras and c-K-ras are the cellular homologs of v-Hand v-K-ras originally isolated from Harvey and Kirsten strains of rat sarcoma viruses. The third family member is designated c-N-ras. Normal cellular ras genes are referred to as protooncogenes and have the potential for activation to oncogenes by mutations occurring in codons 12, 13 and 61. Such mutated, activated and transforming ras genes have been identified and isolated from human tumors and cultured tumor cells. Although the expression patterns of ras proto-oncogene proteins in normal human tissues are known, similar information for activated ras oncogene encoded p21s and their relevance to human disease diagnosis and prognosis remains to be determined.

Type: Primary
Antigen: P21 RAS
Clonality: Monoclonal
Conjugation: Unconjugated
Host: Mouse
Isotype: IgG1
Reactivity: Human
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