Anti-CDKN1B Rabbit Monoclonal Antibody

GTX61772
89364-174EA 556.26 CAD
89364-174
Anti-CDKN1B Rabbit Monoclonal Antibody
p27(Kip1) is a cyclin-dependent kinase inhibitor involved in G1 arrest. p27(Kip1) binds to and inhibits cyclinE-Cdk2 complex, cyclinA-CDK2 and cyclinD1-CDK4 . p27(Kip1) is regulated by phosphorylation on serine 10 (S10) and threonine 187 (T187). Phosphorylation by CDK2 on T187 results in ubiquitylation and degradation of p27(Kip1) ; while phosphorylation by hKIS on S10 signals the nuclear export to the cytoplasm .

Type: Primary
Antigen: CDKN1B
Clonality: Monoclonal
Clone: 0
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity:
Order Now

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Learn more About VWR