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Specifications
- Antibody type:Primary
- Antigen name:Phosphodiesterase 4A8
- Clonality:Polyclonal
- Gene ID:5141
- Host:Rabbit
- Isotype:IgG
- Reactivity:Mouse
- Antigen symbol:PDE4A8
- Conjugation:Unconjugated
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- ImmunoPrecipitation:Yes
- Size:100 μg
- Western blot:Yes
- Antigen synonyms:PDE46,DPDE2,Phosphodiesterse Type 4A8,PDE4,2EL,PDE4A_HUMAN.,Phosphodiesterase 4A,PDE4A
- Storage buffer:Preservative: 0.02% Thimerosal / Merthiolate
- Storage temperature:Keep as concentrated solution. Store at 4 °C short term. For extended storage aliquot and store at –20 °C or below. Avoid freeze-thaw cycles.
- Concentration:1 mg/ml
- Immunogen:N-terminus PDE4A8 synthetic cyclic peptide.
- Tested applications:ICC/IF, IP, WB
- Purification:Immunogen affinity purified
- Cat. no.:89367-340
Specifications
About this item
The PDE4A8 is a testis germ cell-specific PDE4A variant. There are two PDE4A variants identified in rat testis (PDE4A8 and an un-characterized 76 kDa PDE4A protein). Spermatogenesis is accompanied by expression of a varied repertoire of PDE4 enzymes at different stages of cell differentiation that presumably perform specialized functions. Confocal microscopic examination revealed the presence of PDE4A8 in primary and secondary spermatids but not in mature spermatozoa. PDE4A8 inhibition results in increased apoptosis of the germ cells accompanied with reduction in the number of mature spermatozoa.
ICC: Use at a dilution of 1/250. IP: Use at a dilution of 1/250. WB: Use at a dilution of 1/1000. Predicted molecular weight: 106 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Type: Primary
Antigen: PDE4A8
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Mouse