Anti-PRDX2 Rabbit Polyclonal Antibody

Supplier: GeneTex
89360-116EA 711 CAD
Anti-PRDX2 Rabbit Polyclonal Antibody
The Peroxiredoxin (Prdx, Prx, or Trx-Px) family of enzymes is a recently identified family of peroxidases found in free-living organisms. The six known isoforms (Prx1-6) play an important role in protecting lipids, enzymes and DNA against peroxides, such as hydrogen peroxide. The ubiquitously expressed peroxiredoxins have also been shown to play a role in apoptosis and cell differentiation. This is acomplished by the active cysteine of Prx reducing peroxides, which is then converted into a transient cysteine sulfenic acid or cysteine sulfinic acid. If Prx protection is inadequate against peroxidases, the resulting protein and DNA damage may result in neurological disease such as Alzheimer's or DNA damage leading to cancer.

Recommended Starting Dilutions:ICC/IF: 1:500WB: 1:10,000Not tested in other applications. Optimal dilution / concentration should be determined by the end user.

Type: Primary
Antigen: PRDX2
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human
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