Anti-Plasminogen Goat Polyclonal Antibody

89358-286EA 562.83 CAD
Anti-Plasminogen Goat Polyclonal Antibody
Plasminogen is a plasma protein synthesised mostly in the liver. Plasma concentration is usually in the range of 70 - 200mg/L. Plasminogen is activated by tissue-plasminogen activator, urokinase and streptokinase, to form plasmin. Activation results from the cleavage and release of the preactivation peptide. Angiostatin, an internal fragment of plasminogen, is a potent inhibitor of angiogenesis, which selectively inhibits endothelial cell proliferation. Angiostatin potently inhibits tumor growth and can maintain metastatic and primary tumors in a dormant state. It is defined by a balance of proliferation and apoptosis of the tumor cells and is composed of plasminogen first four cringle structures. This molecule is generated by proteolytic cleavage of plasminogen.

Type: Primary
Antigen: Plasminogen
Clonality: Polyclonal
Host: Goat
Isotype: IgG
Reactivity: Human
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