Anti-Plasminogen Mouse Monoclonal Antibody [clone: 4D2]

89350-658EA 517.65 CAD
Anti-Plasminogen Mouse Monoclonal Antibody [clone: 4D2]
Plasminogen is a plasma protein synthesised mostly in the liver. It consists of a single polypeptide chain and has a molecular weight of 88.5 kDa. The plasma concentration is usually in the range of 70 - 200mg/L. Plasminogen is activated by tissue-plasminogen activator, urokinase and streptokinase, to form plasmin. Activation results from the cleavage and release of the preactivation peptide. Plasmin consists of a heavy (A-) chain which contains 5 kringles and a light (B-) chain with the active site. Plasmin is a trypsin-like protease whose natural substrate is fibrin, with binding sites for fibrin residing on the kringles. Plasmin is essential for fibrinolysis and decreased fibrinolytic potential due to congenita ldefects in plasmin can lead to recurring thrombosis, thrombophlebitis and pulmonary embolism.

Type: Primary
Antigen: Plasminogen
Clonality: Monoclonal
Clone: [4D2]
Conjugation: No
Host: Mouse
Isotype: IgG2b
Reactivity: Human
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