Anti-SST Rabbit Polyclonal Antibody

89367-022EA 706.94 CAD
Anti-SST Rabbit Polyclonal Antibody
The cyclic tetradecapeptide somatostatin is widely distributed throughout the body and is an important regulator of endocrine and nervous system function. It exerts its biologic actions by binding to specific high-affinity receptors on the cell surface. Somatostatin inhibits the release of somatotropin. Somatostatin has also been shown in sympathetic nerves, mucosal cells, myenteric nerves of the gastrointestinal tract, salivary glands and in some parafollicular cells of the thyroid. Somatostatin positive cells may also be present in medullary thyroid carcinomas, C-cell hyperplasia, thymic and lung tumors and pulmonary small cell carcinomas.

IHC-P: Use at a dilution of 1/40. Antigen retrieval is not required. This antibody specifically stains the D-cells of the pancreatic islets of Langerhans and tumors arising from these cells. It recognizes somatostatin-containing cells in pancreatic tumors, islet cell hyperplasia and islet cells originating in pancreatic ductules. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.

Type: Primary
Antigen: SST
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human
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