Anti-SRF Mouse Monoclonal Antibody [clone: 1.T.14]

89360-384EA 583.9 CAD
Anti-SRF Mouse Monoclonal Antibody [clone: 1.T.14]
SRF is a transcription factor that binds the serum response element (SRE), a sequence that mediates the transient response of many cellular genes to growth stimulation. SRF binding sites are also constitutive promotor elements in many muscle-specific promoters. At the c-Fos SRE, formation of a ternary complex containing SRF and its accessory protein p62TCF appears to be important for signal transduction. Two related Ets domain proteins, Elk 1 and SRF accessory protein 1 (SAP 1) have DNA binding properties identical to that of p62TCF.

GSA: Use at an assay dependent dilution. This antibody is reported by an independent laboratory to supershift SRF:DNA complexes in EMSA. WB: Use at a concentration of 1 ?g/ml. Detects a band of approximately 67 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.

Type: Primary
Antigen: SRF
Clonality: Monoclonal
Clone: 1.T.14
Conjugation: Unconjugated
Host: Mouse
Isotype: IgG
Reactivity: Human
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