Anti-SRP72 Rabbit Polyclonal Antibody

Supplier: Genetex
89349-662EA 272.33 CAD
Anti-SRP72 Rabbit Polyclonal Antibody
The SRP72 gene encodes the 72-kD subunit of the signal recognition particle (SRP), a ribonucleoprotein complex that mediates the targeting of proteins to the endoplasmic reticulum (ER) (summarized by Lutcke et al., 1993 [PubMed 8388879]). The complex consists of a 7S (or 7SL) RNA and 6 different proteins, SRP9 (MIM 600707), SRP14 (MIM 600708), SRP19 (MIM 182175), SRP54 (MIM 604857), SRP68 (MIM 604858), and SRP72. The proteins are bound to the 7S RNA as monomers (SRP19 and SRP54) or heterodimers (SRP9/SRP14 and SRP68/SRP72). SRP9 and SRP14 constitute the Alu domain of 7S, whereas the other 4 proteins belong to the S domain. SRP has at least 3 distinct functions that can be associated with the protein subunits: signal recognition, translational arrest, and ER membrane targeting by interaction with the docking protein.[supplied by OMIM]

Type: Primary
Antigen: SRP72
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
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