Anti-SNTB2 Mouse Monoclonal Antibody [clone: 1351]

Supplier: GeneTex
89357-966EA 838.68 CAD
Anti-SNTB2 Mouse Monoclonal Antibody [clone: 1351]
Syntrophins are structurally related proteins located at the neuromuscular synapse and play an important role in dystrophin associated protein (DAP) complex formation. To date there have been three distinct syntrophin isoforms discovered: alpha 1, beta 1, and beta 2. These proteins each contain a PDZ domain, a syntrophin-unique domain (SU), and three pleckstrin homology domains (PH1a,1b and 2). The PDZ domain has been shown to be responsible for binding syntrophin to nNOS and the DAP complex. This association results in localization of the nicotinic acetylcholine receptor to the cytoskeleton via the (S/T)XV C terminus.

Recommended Starting Dilutions:ICC/IF: 1:80FACS: 0.5µg per 10^6 cellsIHC: 1:100 - 1:200WB: 1:100 - 1:2000Not tested in other applications. Optimal dilution / concentration should be determined by the end user.

Type: Primary
Antigen: SNTB2
Clonality: Monoclonal
Clone: 1351
Conjugation: Unconjugated
Host: Mouse
Isotype: IgG1
Reactivity: Human, Mouse, Chicken, Dog, Rat, Amphibians, Vertebrates
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