Anti-TOSO / FAIM3 Rabbit Monoclonal Antibody

89364-540EA 585.93 CAD
Anti-TOSO / FAIM3 Rabbit Monoclonal Antibody
Fas apoptotic inhibitory molecule 3 (FAIM3) / TOSO is a single-pass membrane protein that inhibits FAS-induced apoptosis, preventing CASP8 processing through CFLAR up-regulation. FAIM3 / TOSO protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. It seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. FAIM3 / TOSO is specifically expressed in lymph nodes, peripheral blood leukocytes, lung, thymus, and kidneys .

Type: Primary
Antigen: TOSO / FAIM3
Clonality: Monoclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human
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