Anti-TLR8 Mouse Monoclonal Antibody [clone: 44C143]

Supplier: Genetex
89359-186EA 959.66 CAD
Anti-TLR8 Mouse Monoclonal Antibody [clone: 44C143]
The TLR8 protein is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. The TLR8 gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X.

WB: Use at a concentration of 1 - 2 ?g/ml. Detects a band of approximately 120 kDa. FC (Intracellular): 2-5 ug/ 1x10^6 cells Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.

Type: Primary
Antigen: TLR8
Clonality: Monoclonal
Conjugation: Unconjugated
Host: Mouse
Isotype: IgG1
Reactivity: Human
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