Anti-TPO Mouse Monoclonal Antibody [clone: MoAb47]

Supplier: GeneTex

GTX12500
89350-858EA 680.13 CAD
89350-858
Anti-TPO Mouse Monoclonal Antibody [clone: MoAb47]
Antibodies
Thyroid Peroxidase is a transmembrane protein of 107 kDa containing a heme prosthetic group and it is present on the apical surface of the thyroid follicular cells. It is the primary enzyme involved in thyroid hormone synthesis. Malignant thyroid tumors exhibit an anomaly in Thyroid Peroxidase resulting in lower antibody affinity. This antibody may be useful aid in the differentiation between the benign and malignant thyroid tumors.

IHC-P: Use at a dilution of 1/10 - 1/25 in an ABC method. Perform heat mediated antigen retrieval with 1mM EDTA buffer, pH 9.0 before commencing with IHC staining protocol. We suggest an incubation period of 30-60 minutes at room temperature. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.

Type: Primary
Antigen: TPO
Clonality: Monoclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human
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