Furin convertase inhibitor (chloromethylketone)

Supplier: Enzo Life Sciences

Furin convertase inhibitor (chloromethylketone)

Furin convertase inhibitor (chloromethylketone)

260-022-M005 260-022-M001

89146-608EA 441.97 CAD

89146-608 89146-610

Furin convertase inhibitor (chloromethylketone)

Proteins and Peptides

Highly specific, potent, irreversible, and cell-permeable competitive inhibitor of proprotein convertases: furin/SPC1 (Ki~1nM), SPC2/PC2 (Ki=0.36nM), SPC3/PC1/PC3(Ki=2.0nM), SPC4/PACE4 (Ki=3.6nM), SPC6/PC5/PC6, and SPC7/LPC/PC7/PC8 (Ki=0.12nM). Because furin activates viral glycoproteins, this inhibitor is a useful antiviral agent. In addition, it inhibits furin-dependent pro-MMP-2 activation in various cell lines, including U87 and HT1080 cells. Typical concentration range used in tissue culture is 25-100µM.

Highly specific, potent, irreversible, and cell-permeable competitive inhibitor of proprotein convertases.

White to off-white powder.

Soluble in DMSO, methanol or water.

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