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Prostaglandin E2 ≥97%, crystalline powder

Supplier: Enzo Life Sciences
Danger
Synonyms: PGE₂

PG007-0010
Prostanoid receptor ligand

Biosynthesis in numerous cell types. Potent vasodilator. Exerts both anti- and proinflammatory activities by inhibition of mediator release and enhancement of mediator action. Stimulates bone resorption. Synergizes with LTB4. Facilitates replication of AIDS virus. Regulates sleep/wake cycle. Thermoregulatory action in the CNS. Induces LHRH release from rat median eminence. Regulates renal hemodynamics and sodium excretion.One of the primary cyclooxygenase (COX) products of arachidonic acid and one of the most widely investigated prostaglandins. Its activity influences inflammation, fertility and parturition, gastric mucosal integrity and immune modulation. The effects of PGE2 are transduced by at least four distinct receptors designated EP1, EP2, EP3, and EP4. Affinity constants (Kd) of PGE2 for these receptors range from 1-10nM depending on the receptor subtype and tissue.

Its activity influences inflammation, fertility and parturition, gastric mucosal integrity and immune modulation. The effects of PGE2 are transduced by at least four distinct receptors designated EP1, EP2, EP3, and EP4. Affinity constants (Kd) of PGE2 for these receptors range from 1-10nM depending on the receptor subtype and tissue. Regulates vertebrate hematopoietic stem cell homeostasis.

Soluble in 100% ethanol, DMSO or dimethylformamide (100 mg/ml); soluble in acetone. Sparingly soluble in PBS, pH 7.2 (5 mg/ml).

Caution: Stable for at least 2 years after receipt when stored at -20°C. Avoid basic solutions (pH > 7.4), since Prostaglandin E2 will degrade to PGA and PGB. We do not recommend storing aqueous solutions for more than one day.

Formula: C₂₀H₃₂O₅
MW: 352.47 g/mol
Storage Temperature: Freezer
MDL Number: MFCD00077861
CAS Number: 363-24-6
Specification Test Results
Purity ≥97% (Assay)
Appearance White to off-white crystalline powder


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Size Supplier No. VWR Catalog Number Unit Price Quantity
10 mg BML-PG007-0010 89161-450 Each Retrieving Restricted

Temperature sensitive This Item is temperature sensitive and has specific temperature and storage requirements for shipping/delivery. Requires a maximum 2 day delivery.

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