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Parthenolide ≥97% (by TLC)

Supplier: Enzo Life Sciences
Synonyms: 4,5alpha-Epoxy-6beta-hydroxygermacra-1(10),11(13)-dien-12-oic Acid gamma-Lactone

BML-T113-0050 T113-0250
HDAC inhibitor

Sesquiterpene lactone. Widely used as an herbal remedy for arthritis and migraine. Has anti-inflammatory, antisecretory and spasmolytic activity. Specifically inhibits activation of NF-kappaB by preventing the degradation of IkappaBalpha and IkappaBbeta. Inhibits activation of MAP kinase (MAPK/ERK) and generation of leukotriene B4 and thromboxane B2. Potent anticancer agent. Induces apoptosis in various cancer cell lines. Specifically inhibits histone deacetylase 1 (HDAC1) without affecting other class I/II HDACs. Inhibits tubulin carboxypeptidase (TCP) activity.

Isolated from feverfew (Chrysanthemum parthenium) leaves.


Formula: C₁₅H₂₀O₃
MW: 248.32 g/mol
MDL Number: MFCD00134592
CAS Number: 20554-84-1


 

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Size Supplier No. VWR Catalog Number Unit Price Quantity
250 mg BML-T113-0250 89164-980 Each Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

50 mg BML-T113-0050 89164-978 Each Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

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