Anti-BCL2L1 Rabbit Polyclonal Antibody

10078-164EA 811.46 CAD
Anti-BCL2L1 Rabbit Polyclonal Antibody
Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. Bcl-xL is a member of the Bcl-2 family of proteins that are critical regulators of apoptosis. These can be divided into two classes: those that inhibit apoptosis and those that promote cell death. Bcl-xL is an anti-apoptotic mitochondrial protein related to Bcl-w and the major transcript of the bcl-x gene. Its high expression in tumors is correlated with advanced disease and poor prognosis. Bcl-xL expression level increases in response to several stimuli such as ionizing radiation and treatment with chemotherapeutic agents.

BCL2L1 antibody can be used in immunohistochemistry starting at 20 ?g/mL, and flow cytometry.

PBS, 0.02% sodium azide, 50% glycerol.

Aliquot and store at -80°C. Avoid multiple freeze-thaw cycles.

Type: Primary
Antigen: BCL2L1
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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