Anti-DCAF6 Rabbit Polyclonal Antibody

Supplier: ProSci
10076-296EA 1011.8 CAD
Anti-DCAF6 Rabbit Polyclonal Antibody
Principal Names: Nuclear receptor Interacting Protein (NRIP); IQ motif and WD repeats 1 (IQWD1) Official Gene Symbol: IQWD1 Gene ID: 55827 (Human) Gene Map Locus: 1q24.2 (Human) WD-repeat proteins are a large family of eukaryotic proteins coordinating multi-protein complex assemblies and their role has been implicated in multiple cellular processes including signal transduction, transcriptional regulation, cell cycle control and apoptosis. NRIP is a novel 860a.a nuclear protein consisting of seven conserved WD40 domains and one NLS motif. It binds to androgen and glucocorticoid receptors and up regulates their transcriptional activity, thereby functioning as a nuclear receptor coactivator. Role of NRIP has been implicated in cell growth and also in cervical and prostrate cancer thus indicating a therapeutic intervention. Northern Blot analysis detected a high expression of NRIP in skeletal muscle and testis and low expression in heart, prostrate and adrenal gland.

IQWD1 antibody can be used in ELISA, Western Blot, and immunohistochemistry starting at 10 - 20 ?g/mL.

PBS, 0.2% gelatin, 0.05% sodium azide.

Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Type: Primary
Antigen: DCAF6
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Reactivity: Dog, Human, Mouse, Rat
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